Cortisol is the most abundant circulating steroid and the major glucocorticoid secreted by the adrenal cortex. Studies have shown Cortisol is physiologically effective in blood pressure maintenance and anti-inflammatory activity. It is also involved in calcium absorption, gluconeogenesis and the secretion of gastric acid and pepsin.
Most circulating cortisol is bound to cortisol binding protein, transcortin, or albumin. In the absence of cortisol binding proteins in saliva, salivary cortisol is considered to be free and may show a diurnal rhythm with the highest levels in the morning an the lowest levels at night.
Research areas interests include adrenal function, Addisons and Cushings deseases, adrenal hyperplasia, carcinoma, and stress studies.
With our cortisol ELISA kit you can measure in just one hour the cortisol levels in SALIVA samples. Only a small volume of saliva is needed for the analysis (please check the table and the IFU for more detailed information).